MOG Antibody Disease
MOG Antibody Disease (MOGAD) is a rare immune-mediated condition that affects the central nervous system. At the practice of Dr. Ubaid Shah, a leading pediatric neurologist in Dubai, we are committed to providing comprehensive care and the latest information on conditions like MOGAD to help parents and caregivers navigate their child’s health challenges.
What is MOG Antibody Disease (MOGAD)?
MOG Antibody Disease involves the body’s immune system mistakenly attacking myelin oligodendrocyte glycoprotein (MOG), a protein crucial for the proper functioning of the nervous system. This attack leads to inflammation and damage in the brain, spinal cord, and optic nerves, which can manifest in various neurological symptoms.
Symptoms of MOGAD
MOGAD can present differently in children, with symptoms varying widely in terms of both type and severity. Common symptoms include:
- Vision Loss or Disturbances: Often sudden and severe, potentially affecting one or both eyes.
- Weakness: This may occur in the limbs and can be significant, affecting mobility.
- Sensory Changes: Such as numbness or tingling in different parts of the body.
- Coordination Problems: Difficulty with balance and motor functions.
- Bladder and Bowel Issues: Including urgency or incontinence.
- Pain: This can be part of the neurological impact of the disease.
Diagnosis of MOGAD
Diagnosing MOGAD involves a combination of clinical evaluation and advanced diagnostic tools to ensure accuracy and comprehensiveness. Our approach includes:
- MRI Scans: To detect lesions in the brain, spinal cord, or optic nerves.
- Blood Tests: Specifically testing for MOG antibodies.
- Lumbar Puncture: To analyze cerebrospinal fluid for inflammatory markers.
Treatment Options
Treatment for MOGAD aims to manage symptoms, reduce the frequency of flare-ups, and minimize long-term impacts. Treatment plans may include:
- Corticosteroids: To reduce acute inflammation during flare-ups.
- Immunotherapy: Such as rituximab or other medications to modulate the immune response.
- Plasma Exchange (PLEX): Used in severe cases to remove harmful antibodies from the blood.
Our Commitment
Dr. Ubaid Shah and our dedicated team are committed to providing personalized care tailored to the needs of each child. We understand the challenges that come with a diagnosis of MOGAD and are here to support you and your family every step of the way.
